品牌:
美國 NewEast Biosciences
貨號: 26910
抗原:Full Recombinant Active Rheb
規(guī)格:30 微升
產(chǎn)品全名:Anti-Rheb-GTP Mouse Monoclonal Antibody
應(yīng)用: IP, IHC, IF
種屬反應(yīng)性的選擇:Human, Mouse and Rat
物種/宿主:Mouse
描述: Anti-Rheb-GTP Monoclonal Antibody
背景介紹: Small GTPases are a super-family of cellular signaling regulators. Rheb is a member of the Ras-superfamily GTPases. Rheb has been shown to interact with C-Raf, Mammalian target of rapamycin (mTOR), TSC2, Ataxia telangiectasia mutated (ATM), KIAA1303 and Ataxia telangiectasia and Rad3 related (ATR).
免疫原: Recombinant full-length protein of active Rheb.
經(jīng)過測試的應(yīng)用: IP, IHC,IF
推薦稀釋比:
IP: 1 μg for 1~2 mg total cellular proteins
IHC, IF: 1:50-1:250
濃度: 1 mg/ml
宿主: Mouse
形式: Liquid
克隆性: Monoclonal
亞型: IgM
純度: Purified from ascites
防腐劑: No
Constituents: PBS (without Mg2+and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
種屬反應(yīng)性: Anti-Rheb-GTP monoclonal antibody recognizes active Rheb of vertebrates.
儲存條件: Store at -20°C. Avoid freeze/thaw cycles
免疫沉淀/蛋白質(zhì)印跡:
Rheb activation assay. Purified Rheb proteins were immunoprecipitated after treated with GDP (lane 1) or GTPγS (lane 2). Immunoprecipitation was done with the anti-Rheb-GTP monoclonal antibody (Cat. No. 26910). Immunoblot was with an anti-Rheb rabbit polyclonal antibody (Cat. No. 21098).
武漢費斯德生物科技有限公司是美國NewEast Biosciences在中國的辦事處，也是目前所有產(chǎn)品國內(nèi)經(jīng)銷處。
目前客戶使用產(chǎn)品發(fā)表超過1000谷歌學(xué)術(shù)文獻，其中論文分布排名前50刊物上。
NewEast Biosciences 在十二年前率先研發(fā)倆種獨特的抗體。這倆種抗體僅僅識別活性的GTP酶或者突變的Oncogene。 GTP酶涉及(1)響應(yīng)細胞表面受體**的信號轉(zhuǎn)導(dǎo)，包括跨膜受體，例如介導(dǎo)味覺、嗅覺和視覺的那些，（2）核糖體的蛋白質(zhì)生物合成，（3）調(diào)節(jié)細胞分化、增殖、分裂和運動，（4）蛋白質(zhì)通過膜的易位，（5）細胞內(nèi)囊泡的運輸，以及囊泡介導(dǎo)的分泌和攝取，通過GTP酶控制囊泡外殼組裝。Oncogene側(cè)是誘發(fā)癌癥的基因。
更多產(chǎn)品類目和技術(shù)資料可查看：武漢費斯德生物官網(wǎng)。
